- Founded in 1996 -

Our Services:

•     Regulatory Immunotoxicology/Immunotoxicity Testing

   

  •      Functional & Screening Assay

  •     TDAR: ELISA to Quantify Antibody Response to KLH or SRBC

  •     Natural Killer (NK) Cell Assay

  •     Cytotoxic T Lymphocyte (CTL) Assay

  •     Macrophage/Neutrophil Function

  •     Phagocytosis/Respiratory Burst

  •     Immunophenotype Analysis by Flow Cytometry

•    Host Resistance/Infectious Disease Models for Immunotoxicity or Efficacy

   

  •     Influenza Virus in mice and rats

  •     Herpes virus in mice

  •     Murine Cytomegalovirus (MCMV) (primary or Latent viral reactivation studies)

  •     Listeria monocytogenes in mice and rats

  •     Streptococcus pneumoniae in mice and rats   

  •     Candida albicans in mice

  •     Pseudomonas aeruginosa in mice and rats

  •     Escherichia coli in mice and rats

  •     Staphylococcus aureus in mice and rats

  •     Neisseria meningitidis

  •     Syngeneic Tumor Models

•     Developmental Immunotoxicity Testing

•     Hypersensitivity/Irritancy Testing

   

  •     Local Lymph Node Assay (LLNA)

  •    In Vitro Assay for Immediate Hypersensitivity/Histamine

  •    Irritancy Testing

•     Immunogenicity/Vaccine/Biologics

   

  •      Immunoassay Reference Laboratory

  •     Immunoassay Development/Validation/Implementation

  •     Clinical Trial Immunoassay Analysis

  •     Vaccine Efficacy

  •     Neoantigenicity Studies

  •     ADCC and Cell Based Assays

  •     Cell-based Neutralization Assays

•    Ophthalmic Toxicology and Pharmacology

   

  •     Clinical examination and assessment of ocular toxicity

  •     Ocular irritation examination

  •     Electroretinography

  •     Ocular photography

  •     Ocular pharmacology and pharmacokinetics

  •     Ocular drug delivery and device evaluation

•     Microbiology Services

   

  •      Antimicrobial Testing

  •     Antiviral Testing

  •     Compound Screening

  •     Bacterial Identification

•     Immunopharmacology

   

  •     Proof of Concept

  •     ADCC and Cell based Assays

  •     Interferon Bioassays

  •     Immunomodulators

  •     Biological Response Modifiers

  •     Polyclonal Antibody Production

  •     Monoclonal Antibody Development

  •     Immunoglobulin Isotypes and Subclasses 

   

HOME l ABOUT US l SERVICES l CONTACT US

120 First Flight Lane, Morrisville NC 27560

Phone:(919) 719-2500  Fax:(919) 719-2505  E-mail: info@brt-labs.com