In Vivo Services

In Vivo Models for Immune Safety, Function & Therapeutic Efficacy

BRT provides rodent-based models (mouse and rat) to evaluate immune function, host resistance, and therapeutic efficacy. Our in vivo capabilities support customized study designs across immune safety, infectious disease, hypersensitivity, immunopharmacology, and specialized disease models.

In Vivo Research Capabilities

BRT offers specialized rodent models across immune safety, host resistance, therapeutic efficacy, hypersensitivity, and other areas of preclinical research.

Host Resistance & Infectious Disease

Viral, bacterial, and fungal models to evaluate host defense, immune function, and therapeutic response.

Immunotoxicology & Immunosafety

Rodent studies and integrated immune function assessments to evaluate immunotoxicity, immune modulation, and immune safety.

Immunopharmacology & Efficacy

Customized in vivo studies to evaluate therapeutic efficacy, pharmacologic response, and immune-related outcomes.

Hypersensitivity & Allergy Models

In vivo models for hypersensitivity, pulmonary responses, food allergy, histamine response, and related immune endpoints.

Humanized & Immunocompromised Models

Humanized and immunocompromised mouse models supporting studies of human immune responses and therapeutic candidates.

Tumor & Specialized Disease Models

Tumor and specialized inflammatory disease models to support customized efficacy and immune response studies.

Integrated Ex Vivo Assessments

In vivo studies can be integrated with ex vivo assessments to evaluate immune function and provide additional insight into treatment-related responses.

Routes of Exposure

BRT supports a variety of dosing and exposure routes in mouse and rat studies to accomodate customized study designs and research objectives.

Customized In Vivo Research

BRT works with clients to develop customized in vivo study designs based on specific research objectives, test articles, and endpoints. In vivo studies can be integrated with ex vivo and bioanalytical assessments to support individual program needs.