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Humanized Mice

Challenges exist in the ability to predict human drug induced toxicities using animal models for drugs that have human specific targets. Potential toxicities associated with human specific responses may not be identified due to lack of expression of the human specific targets in animal models. BRT has expertise in the utilization of humanized mouse models to evaluate test compounds in the context of human cells, tissues, and biological pathways.

BRT has experienced staff and a dedicated facility consisting of a glass-enclosed animal room with HEPA-filtered air supply for the care and maintenance of immunocompromised mouse models.

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