Services & Capabilities

Immunotoxicity Testing

Our immunotoxicity testing services are designed to detect, quantify, and interpret the potential adverse effects of exposure to pharmaceutical and chemical agents on the immune system. Our state-of-the-art assays can detect changes in immune function and identify potential risks early in the drug development process. We offer a range of assays – including In Vitro, In Vivo, and Ex Vivo models – to help you assess the immune structure and function of your pharmaceutical or biotech products.

Models & Applications
  • Pesticide registration and re-registration immunotoxicity testing
  • T-dependent antibody response (TDAR) in mice and rats
  • Developmental immunotoxicology
  • Aging models
  • IBD – Murine Colitis model for immunopharmacology and toxicology
  • Metabolism studies
  • Abdominal infection
Assays & Platforms
  • Functional & screening assays
  • ELISA to quantify antibody response to KLH, SRBC, TT, HbsAg from TDAR studies
  • SRBC Plaque Forming Cell Assay
  • Natural Killer (NK) Cell Assay
  • Cytotoxic T Lymphocyte (CTL) Assay
  • T Cell Proliferation Assay
  • Macrophage/neutrophil function (cytokine production/bactericidal activity)
  • Phagocytosis/Respiratory Burst
  • Immunophenotyping analysis by flow cytometry
  • In vitro whole blood and PBMC immunomodulation assays

Learn MOre About
Our In Vitro Test Offerings

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