Challenges exist in the ability to predict human drug-induced toxicities using animal models for drugs that have human-specific targets. Potential toxicities associated with human-specific responses may not be identified due to the lack of expression of the human-specific targets in animal models. Our humanized mouse models are an essential tool for studying the human immune system in vivo and evaluating test compounds in the context of human cells, tissues, and biological pathways. At BRT, we offer a range of humanized mouse models that enable you to test the efficacy of immunotherapeutics and evaluate the safety of your drug candidates.

Our experienced staff and AAALAC-accredited vivarium ensure the best care of our humanized mouse models.